Crucial First Steps: The Transcriptional Control of Neuron Delamination

Crucial First Steps: The Transcriptional Control of Neuron Delamination

A crucial event in the birth of a neuron is the detachment of its apical process from the neuroepithelium. In this issue of Neuron, Rousso et al. (2012) show that repression of N-cadherin by Foxp transcription factors disrupts apical adherens junctions and triggers neurogenesis.

control of the optical properties of nanoparticles by laser fields

در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...

Transcriptional control of midbrain dopaminergic neuron development.

Although loss of midbrain dopaminergic neurons is associated with one of the most common human neurological disorders, Parkinson's disease, little is known about the specification of this neuronal subtype. Hence, the recent identification of major transcriptional determinants regulating the development of these neurons has brought much excitement and encouragement to this field. These new findi...

The transcriptional control of trunk neural crest induction, survival, and delamination.

Trunk neural crest cells are generated at the border between the neural plate and nonneural ectoderm, where they initiate a distinct program of gene expression, undergo an epithelial-mesenchymal transition (EMT), and delaminate from the neuroepithelium. Here, we provide evidence that members of three families of transcription induce these properties in premigratory neural crest cells. Sox9 acts...

the Control of Emerging Infectious Diseases: First Steps